Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3632688..3633502 Replicon chromosome
Accession NZ_CP103771
Organism Salmonella enterica strain S1905

Toxin (Protein)


Gene name TacT3 Uniprot ID A0A3G3DUX8
Locus tag NYS49_RS17705 Protein ID WP_000971653.1
Coordinates 3632975..3633502 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID M7S6I2
Locus tag NYS49_RS17700 Protein ID WP_000855694.1
Coordinates 3632688..3632978 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYS49_RS17670 (3628629) 3628629..3629279 - 651 WP_023166786.1 type III secretion system transcriptional activator InvF -
NYS49_RS17675 (3629736) 3629736..3630179 + 444 WP_000715096.1 SPI-1 type III secretion system invasion lipoprotein InvH -
NYS49_RS17680 (3630598) 3630598..3631047 + 450 WP_000381616.1 hypothetical protein -
NYS49_RS17685 (3631032) 3631032..3631379 + 348 WP_001555786.1 DUF1493 family protein -
NYS49_RS17690 (3631651) 3631651..3631977 - 327 WP_000393297.1 hypothetical protein -
NYS49_RS17695 (3632218) 3632218..3632418 + 201 Protein_3453 IS3 family transposase -
NYS49_RS17700 (3632688) 3632688..3632978 + 291 WP_000855694.1 DUF1778 domain-containing protein Antitoxin
NYS49_RS17705 (3632975) 3632975..3633502 + 528 WP_000971653.1 GNAT family N-acetyltransferase Toxin
NYS49_RS17710 (3633575) 3633575..3633777 - 203 Protein_3456 IS5/IS1182 family transposase -
NYS49_RS17715 (3634127) 3634127..3634783 + 657 WP_000420449.1 protein-serine/threonine phosphatase -
NYS49_RS17720 (3635028) 3635028..3635522 - 495 WP_000424947.1 hypothetical protein -
NYS49_RS17725 (3635549) 3635549..3636217 - 669 WP_023137848.1 hypothetical protein -
NYS49_RS17730 (3636374) 3636374..3636592 - 219 Protein_3460 hypothetical protein -
NYS49_RS17735 (3636803) 3636803..3637201 - 399 Protein_3461 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3633575..3633715 140


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19043.87 Da        Isoelectric Point: 9.7032

>T256630 WP_000971653.1 NZ_CP103771:3632975-3633502 [Salmonella enterica]
MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTTKTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISK
GLGRHDVPVFRLGRLAVDKSMQGQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
SFKTLYAALSASGRL

Download         Length: 528 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10664.50 Da        Isoelectric Point: 6.3133

>AT256630 WP_000855694.1 NZ_CP103771:3632688-3632978 [Salmonella enterica]
MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVSNVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAP
NEKLLAAAFALPDMKK

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G3DUX8

Antitoxin

Source ID Structure
AlphaFold DB A0A3V8SJE7

References