Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 419505..420004 Replicon chromosome
Accession NC_016052
Organism Tetragenococcus halophilus NBRC 12172

Toxin (Protein)


Gene name relE Uniprot ID A0A091C6L0
Locus tag TEH_RS01970 Protein ID WP_014123805.1
Coordinates 419735..420004 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A091CDY2
Locus tag TEH_RS01965 Protein ID WP_014123804.1
Coordinates 419505..419738 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-70)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10511.30 Da        Isoelectric Point: 10.8418

>T25663 WP_014123805.1 NC_016052:419735-420004 [Tetragenococcus halophilus NBRC 12172]
MTFHVETTRRFDKQLKKLDKFAANTILKWLDKNIEGSNNPRLMGKPLVGNHSGKWRYRIGSYRVITKVDDEKLIILALEV
GHRKDIYRK

Download         Length: 270 bp

>T25663 NC_016052:419735-420004 [Tetragenococcus halophilus NBRC 12172]
ATGACTTTTCATGTAGAGACAACTCGTAGGTTCGATAAGCAATTAAAAAAATTAGACAAATTTGCTGCAAACACTATACT
TAAGTGGCTTGATAAAAATATTGAAGGAAGCAATAATCCAAGATTGATGGGTAAACCGCTCGTTGGAAATCACTCTGGGA
AATGGCGCTATCGAATAGGAAGTTATCGTGTGATTACCAAGGTTGACGACGAAAAATTAATTATTTTAGCTTTAGAAGTA
GGGCACAGGAAAGATATTTATAGAAAATAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8599.41 Da        Isoelectric Point: 3.8597

>AT25663 WP_014123804.1 NC_016052:419505-419738 [Tetragenococcus halophilus NBRC 12172]
MATITVRVTDEEKDFLDNMAKFEGKSLSELLKTTTLSSLEDAYDAQIGDAAYDEYLKNPQSRPLSESLEEYGLGESE

Download         Length: 234 bp

>AT25663 NC_016052:419505-419738 [Tetragenococcus halophilus NBRC 12172]
ATGGCTACTATTACTGTACGCGTTACTGATGAAGAAAAAGATTTTTTAGATAATATGGCAAAGTTTGAGGGAAAGAGTTT
GTCTGAACTATTAAAGACTACAACGCTGTCATCTTTAGAAGACGCCTATGATGCACAAATTGGGGATGCAGCTTATGATG
AGTATTTGAAAAATCCGCAATCCCGTCCTCTGTCAGAATCATTAGAGGAATACGGCTTAGGAGAGAGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A091C6L0

Antitoxin

Source ID Structure
AlphaFold DB A0A091CDY2

References