Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2131604..2131872 Replicon chromosome
Accession NZ_CP103742
Organism Escherichia coli O25b:H4-ST131 strain 2822

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2131732..2131834 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2131604..2131872 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R22_RS10165 2128157..2128819 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5R22_RS10170 2128843..2129499 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
M5R22_RS10175 2129601..2129831 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5R22_RS10180 2129970..2130344 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5R22_RS10185 2130348..2131220 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
M5R22_RS10190 2131233..2131574 + 342 WP_000976472.1 YebY family protein -
- 2131604..2131872 - 269 - - Antitoxin
- 2131732..2131834 + 103 - - Toxin
M5R22_RS10195 2131969..2132625 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
M5R22_RS10200 2132626..2132817 - 192 WP_001296140.1 YebW family protein -
M5R22_RS10205 2132922..2133158 - 237 WP_001295499.1 YebV family protein -
M5R22_RS10210 2133275..2134714 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256453 NZ_CP103742:2131732-2131834 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT256453 NZ_CP103742:c2131872-2131604 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References