Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4476021..4476382 Replicon chromosome
Accession NC_016010
Organism Xanthomonas axonopodis pv. citrumelo F1 (Xanthomonas alfalfae)

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XACM_RS19085 Protein ID WP_005914328.1
Coordinates 4476021..4476155 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q3BN31
Locus tag XACM_RS19090 Protein ID WP_011348912.1
Coordinates 4476230..4476382 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XACM_RS19070 4473056..4474078 - 1023 WP_014091330.1 MBL fold metallo-hydrolase -
XACM_RS19075 4474129..4475418 - 1290 WP_011348911.1 tryptophan--tRNA ligase -
XACM_RS19080 4475584..4475793 - 210 WP_003486601.1 CsbD family protein -
XACM_RS19085 4476021..4476155 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XACM_RS19090 4476230..4476382 - 153 WP_011348912.1 entericidin A/B family lipoprotein Antitoxin
XACM_RS19095 4476489..4477412 - 924 WP_008576436.1 arginase -
XACM_RS19100 4477733..4478185 + 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
XACM_RS19105 4478249..4478608 + 360 WP_003486613.1 hypothetical protein -
XACM_RS19110 4478705..4479622 + 918 WP_008576439.1 hypothetical protein -
XACM_RS19115 4479619..4480161 + 543 WP_003486615.1 GTPase -
XACM_RS19120 4480632..4481312 + 681 WP_014091332.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T25645 WP_005914328.1 NC_016010:c4476155-4476021 [Xanthomonas axonopodis pv. citrumelo F1]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T25645 NC_016010:c4476155-4476021 [Xanthomonas axonopodis pv. citrumelo F1]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGCGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5123.06 Da        Isoelectric Point: 8.2782

>AT25645 WP_011348912.1 NC_016010:c4476382-4476230 [Xanthomonas axonopodis pv. citrumelo F1]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT25645 NC_016010:c4476382-4476230 [Xanthomonas axonopodis pv. citrumelo F1]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCGACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2W7I0

References