Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 69350..69897 Replicon chromosome
Accession NC_016010
Organism Xanthomonas axonopodis pv. citrumelo F1 (Xanthomonas alfalfae)

Toxin (Protein)


Gene name relE Uniprot ID A0A2S7EAJ7
Locus tag XACM_RS00275 Protein ID WP_041469944.1
Coordinates 69595..69897 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S7EAN3
Locus tag XACM_RS00270 Protein ID WP_014088897.1
Coordinates 69350..69607 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XACM_RS00255 64501..65952 - 1452 WP_041469194.1 ribonuclease H-like domain-containing protein -
XACM_RS00260 65949..68444 - 2496 WP_014088896.1 DEAD/DEAH box helicase -
XACM_RS00265 68622..69284 + 663 WP_011345814.1 hemolysin III family protein -
XACM_RS00270 69350..69607 + 258 WP_014088897.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
XACM_RS00275 69595..69897 + 303 WP_041469944.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XACM_RS00280 70080..70979 - 900 WP_014088899.1 SDR family NAD(P)-dependent oxidoreductase -
XACM_RS00285 71039..71776 - 738 WP_014088900.1 SDR family oxidoreductase -
XACM_RS00290 71902..72813 + 912 WP_014088901.1 LysR family transcriptional regulator -
XACM_RS00295 72868..73962 - 1095 WP_014088902.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11551.38 Da        Isoelectric Point: 9.0387

>T25644 WP_041469944.1 NC_016010:69595-69897 [Xanthomonas axonopodis pv. citrumelo F1]
MAEIIWSVPALADLDAIADYIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQH
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

>T25644 NC_016010:69595-69897 [Xanthomonas axonopodis pv. citrumelo F1]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCGATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGGCGCTGGTCAAATGGGTGTTGCCGCAGGTCGAGCGATTGATTGAACACCCGGACAGCGGAAGCCGGC
CACAGGAACTCCAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCAC
ATTGTGCTGGTGCACGTCATGCGGTGGGAGCGTGCGCTTCGCAGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9683.17 Da        Isoelectric Point: 10.0778

>AT25644 WP_014088897.1 NC_016010:69350-69607 [Xanthomonas axonopodis pv. citrumelo F1]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLSNAYLVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT25644 NC_016010:69350-69607 [Xanthomonas axonopodis pv. citrumelo F1]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTATCCAATGCCTATCTGGTGGATGTTGCCAGCGATGAGCGCATGCAGCAGCGCATTGCGC
TCCTGGAAGGAATCGCCCGTGGAGAAATGGCAGTCGCGCAAGGCCGTACGCTGCGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S7EAJ7

Antitoxin

Source ID Structure
AlphaFold DB A0A2S7EAN3

References