Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012972..2013117 Replicon chromosome
Accession NZ_CP103731
Organism Klebsiella pneumoniae strain 913

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013008..2013110 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012972..2013117 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T23_RS09770 2008102..2010162 + 2061 WP_004151449.1 oligopeptidase B -
M5T23_RS09775 2010166..2010825 - 660 WP_020324964.1 exodeoxyribonuclease X -
M5T23_RS09780 2010904..2011134 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T23_RS09785 2011247..2011621 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T23_RS09790 2011625..2012494 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M5T23_RS09795 2012511..2012849 + 339 WP_002911404.1 YebY family protein -
- 2012972..2013117 - 146 - - Antitoxin
- 2013008..2013110 + 103 - - Toxin
M5T23_RS09800 2013486..2013629 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T23_RS09805 2013734..2014702 - 969 WP_004151446.1 VirK/YbjX family protein -
M5T23_RS09810 2014859..2015512 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M5T23_RS09815 2015509..2015700 - 192 WP_002911395.1 YebW family protein -
M5T23_RS09820 2015798..2016037 - 240 WP_002911393.1 YebV family protein -
M5T23_RS09825 2016153..2017586 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256405 NZ_CP103731:2013008-2013110 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256405 NZ_CP103731:c2013117-2012972 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References