Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917536..1917681 Replicon chromosome
Accession NZ_CP103729
Organism Klebsiella pneumoniae strain 197

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917572..1917674 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917536..1917681 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R33_RS09450 1912666..1914726 + 2061 WP_004151449.1 oligopeptidase B -
M5R33_RS09455 1914730..1915389 - 660 WP_021440386.1 exodeoxyribonuclease X -
M5R33_RS09460 1915468..1915698 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5R33_RS09465 1915811..1916185 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5R33_RS09470 1916189..1917058 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
M5R33_RS09475 1917075..1917413 + 339 WP_002911404.1 YebY family protein -
- 1917536..1917681 - 146 - - Antitoxin
- 1917572..1917674 + 103 - - Toxin
M5R33_RS09480 1918049..1918192 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5R33_RS09485 1918297..1919265 - 969 WP_004151446.1 VirK/YbjX family protein -
M5R33_RS09490 1919422..1920075 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
M5R33_RS09495 1920072..1920263 - 192 WP_002911395.1 YebW family protein -
M5R33_RS09500 1920361..1920600 - 240 WP_002911393.1 YebV family protein -
M5R33_RS09505 1920716..1922149 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256391 NZ_CP103729:1917572-1917674 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256391 NZ_CP103729:c1917681-1917536 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References