Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1856867..1857012 Replicon chromosome
Accession NZ_CP103727
Organism Klebsiella pneumoniae strain 2289

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1856903..1857005 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1856867..1857012 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T50_RS09100 1851997..1854057 + 2061 WP_004151449.1 oligopeptidase B -
M5T50_RS09105 1854061..1854720 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5T50_RS09110 1854799..1855029 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T50_RS09115 1855142..1855516 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T50_RS09120 1855520..1856389 + 870 WP_128337570.1 copper homeostasis membrane protein CopD -
M5T50_RS09125 1856406..1856744 + 339 WP_016529031.1 YebY family protein -
- 1856867..1857012 - 146 - - Antitoxin
- 1856903..1857005 + 103 - - Toxin
M5T50_RS09130 1857380..1857523 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T50_RS09135 1857628..1858596 - 969 WP_074426446.1 VirK/YbjX family protein -
M5T50_RS09140 1858753..1859406 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M5T50_RS09145 1859403..1859594 - 192 WP_002911395.1 YebW family protein -
M5T50_RS09150 1859692..1859931 - 240 WP_002911393.1 YebV family protein -
M5T50_RS09155 1860047..1861480 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256376 NZ_CP103727:1856903-1857005 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256376 NZ_CP103727:c1857012-1856867 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References