Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1841450..1841595 Replicon chromosome
Accession NZ_CP103714
Organism Klebsiella pneumoniae strain ST15

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1841486..1841588 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1841450..1841595 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T51_RS08865 1836580..1838640 + 2061 WP_004151449.1 oligopeptidase B -
M5T51_RS08870 1838644..1839303 - 660 WP_020324964.1 exodeoxyribonuclease X -
M5T51_RS08875 1839382..1839612 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T51_RS08880 1839725..1840099 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T51_RS08885 1840103..1840972 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
M5T51_RS08890 1840989..1841327 + 339 WP_002911404.1 YebY family protein -
- 1841450..1841595 - 146 - - Antitoxin
- 1841486..1841588 + 103 - - Toxin
M5T51_RS08895 1841964..1842107 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T51_RS08900 1842212..1843180 - 969 WP_004151446.1 VirK/YbjX family protein -
M5T51_RS08905 1843337..1843990 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M5T51_RS08910 1843987..1844178 - 192 WP_002911395.1 YebW family protein -
M5T51_RS08915 1844276..1844515 - 240 WP_002911393.1 YebV family protein -
M5T51_RS08920 1844631..1846064 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256306 NZ_CP103714:1841486-1841588 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256306 NZ_CP103714:c1841595-1841450 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References