Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 718566..718711 Replicon chromosome
Accession NZ_CP103697
Organism Klebsiella pneumoniae strain ST3576

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 718602..718704 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 718566..718711 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R27_RS03310 (M5R27_03310) 713696..715756 + 2061 WP_004148850.1 oligopeptidase B -
M5R27_RS03315 (M5R27_03315) 715760..716419 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5R27_RS03320 (M5R27_03320) 716498..716728 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5R27_RS03325 (M5R27_03325) 716841..717215 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5R27_RS03330 (M5R27_03330) 717219..718088 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
M5R27_RS03335 (M5R27_03335) 718105..718443 + 339 WP_002911404.1 YebY family protein -
- 718566..718711 - 146 - - Antitoxin
- 718602..718704 + 103 - - Toxin
M5R27_RS03340 (M5R27_03340) 719079..719222 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5R27_RS03345 (M5R27_03345) 719327..720295 - 969 WP_004151446.1 VirK/YbjX family protein -
M5R27_RS03350 (M5R27_03350) 720452..721105 + 654 WP_121915274.1 protein-serine/threonine phosphatase -
M5R27_RS03355 (M5R27_03355) 721102..721293 - 192 WP_002911395.1 YebW family protein -
M5R27_RS03360 (M5R27_03360) 721391..721630 - 240 WP_002911393.1 YebV family protein -
M5R27_RS03365 (M5R27_03365) 721746..723179 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256217 NZ_CP103697:718602-718704 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256217 NZ_CP103697:c718711-718566 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References