Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1986225..1986370 Replicon chromosome
Accession NZ_CP103687
Organism Klebsiella pneumoniae strain ST307

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1986261..1986363 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1986225..1986370 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S48_RS09745 1981355..1983415 + 2061 WP_004148850.1 oligopeptidase B -
M5S48_RS09750 1983419..1984078 - 660 WP_032435029.1 exodeoxyribonuclease X -
M5S48_RS09755 1984157..1984387 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S48_RS09760 1984500..1984874 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S48_RS09765 1984878..1985747 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5S48_RS09770 1985764..1986102 + 339 WP_002911404.1 YebY family protein -
- 1986225..1986370 - 146 - - Antitoxin
- 1986261..1986363 + 103 - - Toxin
M5S48_RS09775 1986738..1986881 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S48_RS09780 1986986..1987954 - 969 WP_004151446.1 VirK/YbjX family protein -
M5S48_RS09785 1988111..1988764 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5S48_RS09790 1988761..1988952 - 192 WP_002911395.1 YebW family protein -
M5S48_RS09795 1989050..1989289 - 240 WP_002911393.1 YebV family protein -
M5S48_RS09800 1989405..1990838 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256182 NZ_CP103687:1986261-1986363 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256182 NZ_CP103687:c1986370-1986225 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References