Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2689499..2689697 Replicon chromosome
Accession NZ_CP103679
Organism Enterobacter hormaechei strain MB4528 Variant

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2689501..2689604 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2689499..2689697 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T06_RS12775 (M5T06_12775) 2685113..2687091 + 1979 Protein_2499 DNA cytosine methyltransferase -
M5T06_RS12780 (M5T06_12780) 2687183..2687398 + 216 WP_063847882.1 TraR/DksA family transcriptional regulator -
M5T06_RS12785 (M5T06_12785) 2687455..2687976 + 522 WP_049125635.1 hypothetical protein -
M5T06_RS12790 (M5T06_12790) 2688097..2688369 + 273 WP_063847881.1 excisionase -
M5T06_RS12795 (M5T06_12795) 2688338..2689423 + 1086 WP_059364220.1 phage integrase Arm DNA-binding domain-containing protein -
- 2689499..2689697 + 199 - - Antitoxin
- 2689501..2689604 - 104 - - Toxin
M5T06_RS12800 (M5T06_12800) 2689746..2690084 - 339 WP_033486805.1 YebY family protein -
M5T06_RS12805 (M5T06_12805) 2690101..2690970 - 870 WP_017384341.1 copper homeostasis membrane protein CopD -
M5T06_RS12810 (M5T06_12810) 2690972..2691343 - 372 WP_023296802.1 CopC domain-containing protein YobA -
M5T06_RS12815 (M5T06_12815) 2691481..2691711 + 231 WP_003859784.1 DNA polymerase III subunit theta -
M5T06_RS12820 (M5T06_12820) 2691823..2692473 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
M5T06_RS12825 (M5T06_12825) 2692497..2693159 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrA / gtrB 2657113..2695216 38103


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T256148 NZ_CP103679:c2689604-2689501 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 199 bp

>AT256148 NZ_CP103679:2689499-2689697 [Enterobacter hormaechei]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTGGTCTG
AAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References