Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1862..2397 Replicon plasmid pMB4861_1
Accession NZ_CP103675
Organism Enterobacter hormaechei strain 1074

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M5T14_RS22245 Protein ID WP_259385504.1
Coordinates 2110..2397 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M5T14_RS22240 Protein ID WP_235423158.1
Coordinates 1862..2113 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T14_RS22235 (M5T14_22235) 1282..1655 - 374 Protein_1 site-specific integrase -
M5T14_RS22240 (M5T14_22240) 1862..2113 + 252 WP_235423158.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
M5T14_RS22245 (M5T14_22245) 2110..2397 + 288 WP_259385504.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M5T14_RS22250 (M5T14_22250) 2664..4574 + 1911 WP_259385505.1 NACHT domain-containing protein -
M5T14_RS22255 (M5T14_22255) 4742..5731 + 990 WP_259385506.1 tyrosine-type recombinase/integrase -
M5T14_RS22260 (M5T14_22260) 5895..6038 - 144 Protein_6 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
M5T14_RS22265 (M5T14_22265) 6089..6328 - 240 WP_259385507.1 type II toxin-antitoxin system antitoxin RelB -
M5T14_RS22270 (M5T14_22270) 6646..6963 + 318 WP_259385508.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..86737 86737


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11002.00 Da        Isoelectric Point: 10.2278

>T256126 WP_259385504.1 NZ_CP103675:2110-2397 [Enterobacter hormaechei]
MTYTVKFRDDALKEWHKLDKAIQQQFAKKLKKCCGNPHIPSAKLCGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSDVYNLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9198.46 Da        Isoelectric Point: 4.2108

>AT256126 WP_235423158.1 NZ_CP103675:1862-2113 [Enterobacter hormaechei]
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPAELYEKMLDALDDQELVKLVAERSKQQLHDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References