Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2794767..2795038 Replicon chromosome
Accession NZ_CP103673
Organism Escherichia coli strain 4069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2794805..2794908 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2794767..2795038 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M4U10_RS13285 2791924..2793363 + 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M4U10_RS13290 2793481..2793717 + 237 WP_001295499.1 YebV family protein -
M4U10_RS13295 2793822..2794013 + 192 WP_001296140.1 YebW family protein -
M4U10_RS13300 2794014..2794670 - 657 WP_001551231.1 protein-serine/threonine phosphatase -
- 2794767..2795038 + 272 - - Antitoxin
- 2794805..2794908 - 104 - - Toxin
M4U10_RS13305 2795066..2795407 - 342 WP_000976472.1 YebY family protein -
M4U10_RS13310 2795420..2796292 - 873 WP_001551232.1 copper homeostasis membrane protein CopD -
M4U10_RS13315 2796296..2796670 - 375 WP_000168747.1 CopC domain-containing protein YobA -
M4U10_RS13320 2796809..2797039 + 231 WP_000916763.1 DNA polymerase III subunit theta -
M4U10_RS13325 2797141..2797797 + 657 WP_076797519.1 carbon-nitrogen hydrolase family protein YobB -
M4U10_RS13330 2797821..2798483 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2786537..2818823 32286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T256103 NZ_CP103673:c2794908-2794805 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT256103 NZ_CP103673:2794767-2795038 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References