Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2422084..2422352 | Replicon | chromosome |
| Accession | NZ_CP103672 | ||
| Organism | Escherichia coli O25b:H4-ST131 strain 4433 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2422212..2422314 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2422084..2422352 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5S92_RS12040 | 2418637..2419299 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| M5S92_RS12045 | 2419323..2419979 | - | 657 | WP_000011664.1 | carbon-nitrogen hydrolase family protein YobB | - |
| M5S92_RS12050 | 2420081..2420311 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| M5S92_RS12055 | 2420450..2420824 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| M5S92_RS12060 | 2420828..2421700 | + | 873 | WP_000879317.1 | copper homeostasis membrane protein CopD | - |
| M5S92_RS12065 | 2421713..2422054 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2422084..2422352 | - | 269 | - | - | Antitoxin |
| - | 2422212..2422314 | + | 103 | - | - | Toxin |
| M5S92_RS12070 | 2422449..2423105 | + | 657 | WP_000812745.1 | protein-serine/threonine phosphatase | - |
| M5S92_RS12075 | 2423106..2423297 | - | 192 | WP_001296140.1 | YebW family protein | - |
| M5S92_RS12080 | 2423402..2423638 | - | 237 | WP_001295499.1 | YebV family protein | - |
| M5S92_RS12085 | 2423755..2425194 | - | 1440 | WP_001296139.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2341535..2438191 | 96656 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T256077 NZ_CP103672:2422212-2422314 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT256077 NZ_CP103672:c2422352-2422084 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
