Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2201204..2201475 Replicon chromosome
Accession NZ_CP103657
Organism Escherichia coli strain 3150

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2201334..2201437 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2201204..2201475 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R25_RS10375 2197759..2198421 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5R25_RS10380 2198445..2199101 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
M5R25_RS10385 2199203..2199433 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5R25_RS10390 2199572..2199946 + 375 WP_022645803.1 CopC domain-containing protein YobA -
M5R25_RS10395 2199950..2200822 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
M5R25_RS10400 2200835..2201176 + 342 WP_000976472.1 YebY family protein -
- 2201204..2201475 - 272 - - Antitoxin
- 2201334..2201437 + 104 - - Toxin
M5R25_RS10405 2201572..2202228 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
M5R25_RS10410 2202229..2202420 - 192 WP_001296140.1 YebW family protein -
M5R25_RS10415 2202525..2202761 - 237 WP_001295499.1 YebV family protein -
M5R25_RS10420 2202879..2204318 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T256046 NZ_CP103657:2201334-2201437 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT256046 NZ_CP103657:c2201475-2201204 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References