Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1986013..1986158 Replicon chromosome
Accession NZ_CP103654
Organism Klebsiella pneumoniae strain 1159

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1986049..1986151 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1986013..1986158 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S75_RS09730 1981143..1983203 + 2061 WP_004148850.1 oligopeptidase B -
M5S75_RS09735 1983207..1983866 - 660 WP_032435029.1 exodeoxyribonuclease X -
M5S75_RS09740 1983945..1984175 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S75_RS09745 1984288..1984662 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S75_RS09750 1984666..1985535 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5S75_RS09755 1985552..1985890 + 339 WP_002911404.1 YebY family protein -
- 1986013..1986158 - 146 - - Antitoxin
- 1986049..1986151 + 103 - - Toxin
M5S75_RS09760 1986526..1986669 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S75_RS09765 1986774..1987742 - 969 WP_004151446.1 VirK/YbjX family protein -
M5S75_RS09770 1987899..1988552 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5S75_RS09775 1988549..1988740 - 192 WP_002911395.1 YebW family protein -
M5S75_RS09780 1988838..1989077 - 240 WP_002911393.1 YebV family protein -
M5S75_RS09785 1989193..1990626 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T256027 NZ_CP103654:1986049-1986151 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT256027 NZ_CP103654:c1986158-1986013 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References