Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1021818..1022533 Replicon chromosome
Accession NZ_CP103642
Organism Enterobacter hormaechei strain 4453

Toxin (Protein)


Gene name ypjF Uniprot ID A0A8I0UM05
Locus tag M5S55_RS04875 Protein ID WP_023303149.1
Coordinates 1022165..1022533 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID A0A8I0UJV2
Locus tag M5S55_RS04870 Protein ID WP_023303148.1
Coordinates 1021818..1022144 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S55_RS04845 (M5S55_04845) 1016852..1018117 + 1266 WP_023303143.1 hypothetical protein -
M5S55_RS04850 (M5S55_04850) 1018426..1018860 + 435 WP_023303144.1 hypothetical protein -
M5S55_RS04855 (M5S55_04855) 1018919..1019758 + 840 WP_023303145.1 hypothetical protein -
M5S55_RS04860 (M5S55_04860) 1020448..1021269 + 822 WP_023303146.1 DUF932 domain-containing protein -
M5S55_RS04865 (M5S55_04865) 1021335..1021805 + 471 WP_023303147.1 DNA repair protein RadC -
M5S55_RS04870 (M5S55_04870) 1021818..1022144 + 327 WP_023303148.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
M5S55_RS04875 (M5S55_04875) 1022165..1022533 + 369 WP_023303149.1 TA system toxin CbtA family protein Toxin
M5S55_RS04880 (M5S55_04880) 1022599..1022778 + 180 WP_050582484.1 hypothetical protein -
M5S55_RS04885 (M5S55_04885) 1023299..1023457 + 159 WP_023303150.1 hypothetical protein -
M5S55_RS04890 (M5S55_04890) 1023615..1023857 + 243 WP_023303151.1 hypothetical protein -
M5S55_RS04895 (M5S55_04895) 1023879..1024052 - 174 WP_223862021.1 YecR family lipoprotein -
M5S55_RS04900 (M5S55_04900) 1024344..1024700 + 357 WP_045608302.1 hypothetical protein -
M5S55_RS04905 (M5S55_04905) 1024788..1025348 - 561 WP_023303153.1 tyrosine-type recombinase/integrase -
M5S55_RS04910 (M5S55_04910) 1026861..1027037 + 177 WP_013098603.1 hypothetical protein -
M5S55_RS04915 (M5S55_04915) 1027034..1027192 + 159 WP_023303154.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1000900..1041208 40308


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13727.91 Da        Isoelectric Point: 8.2822

>T255982 WP_023303149.1 NZ_CP103642:1022165-1022533 [Enterobacter hormaechei]
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGIILADAVNFLVDKYELVRIDRRGF
SSQGQVPYLTVTDILHARRACGLMKSCSYREVSNIVLSHSRQ

Download         Length: 369 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12215.04 Da        Isoelectric Point: 7.0266

>AT255982 WP_023303148.1 NZ_CP103642:1021818-1022144 [Enterobacter hormaechei]
MSLIPAHEWGIKSDIVPRLGVRLVQEGNRLHYLADRASITGKFSDAECLKLDIVFPHFIRQMESMLTTGEMNSRHAHCVT
LYHNGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References