Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1968386..1968532 Replicon chromosome
Accession NZ_CP103639
Organism Klebsiella aerogenes strain 722

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1968421..1968524 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1968386..1968532 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T48_RS09205 (M5T48_09205) 1963495..1965555 + 2061 WP_032705952.1 oligopeptidase B -
M5T48_RS09210 (M5T48_09210) 1965558..1966217 - 660 WP_015366006.1 exodeoxyribonuclease X -
M5T48_RS09215 (M5T48_09215) 1966297..1966527 - 231 WP_015366007.1 DNA polymerase III subunit theta -
M5T48_RS09220 (M5T48_09220) 1966662..1967036 + 375 WP_015366008.1 CopC domain-containing protein YobA -
M5T48_RS09225 (M5T48_09225) 1967040..1967909 + 870 WP_032705951.1 copper homeostasis membrane protein CopD -
M5T48_RS09230 (M5T48_09230) 1967923..1968264 + 342 WP_015366010.1 YebY family protein -
- 1968386..1968532 - 147 - - Antitoxin
- 1968421..1968524 + 104 - - Toxin
M5T48_RS09235 (M5T48_09235) 1968652..1969605 - 954 WP_072207417.1 spore coat U domain-containing protein -
M5T48_RS09240 (M5T48_09240) 1969618..1971942 - 2325 WP_032705949.1 fimbria/pilus outer membrane usher protein -
M5T48_RS09245 (M5T48_09245) 1971945..1972694 - 750 WP_015366013.1 molecular chaperone -
M5T48_RS09250 (M5T48_09250) 1972712..1973230 - 519 WP_015366014.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255973 NZ_CP103639:1968421-1968524 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 147 bp

>AT255973 NZ_CP103639:c1968532-1968386 [Klebsiella aerogenes]
TAATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References