Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974059..1974204 Replicon chromosome
Accession NZ_CP103635
Organism Klebsiella pneumoniae strain 3221

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974095..1974197 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974059..1974204 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T10_RS09655 1969189..1971249 + 2061 WP_004148850.1 oligopeptidase B -
M5T10_RS09660 1971253..1971912 - 660 WP_032435029.1 exodeoxyribonuclease X -
M5T10_RS09665 1971991..1972221 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T10_RS09670 1972334..1972708 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T10_RS09675 1972712..1973581 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5T10_RS09680 1973598..1973936 + 339 WP_002911404.1 YebY family protein -
- 1974059..1974204 - 146 - - Antitoxin
- 1974095..1974197 + 103 - - Toxin
M5T10_RS09685 1974572..1974715 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T10_RS09690 1974820..1975788 - 969 WP_004151446.1 VirK/YbjX family protein -
M5T10_RS09695 1975945..1976598 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5T10_RS09700 1976595..1976786 - 192 WP_002911395.1 YebW family protein -
M5T10_RS09705 1976884..1977123 - 240 WP_002911393.1 YebV family protein -
M5T10_RS09710 1977239..1978672 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255958 NZ_CP103635:1974095-1974197 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255958 NZ_CP103635:c1974204-1974059 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References