Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2101548..2101819 Replicon chromosome
Accession NZ_CP103626
Organism Escherichia coli strain 4012

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2101678..2101781 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2101548..2101819 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S78_RS10175 2098103..2098765 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5S78_RS10180 2098789..2099445 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
M5S78_RS10185 2099547..2099777 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5S78_RS10190 2099916..2100290 + 375 WP_000204699.1 CopC domain-containing protein YobA -
M5S78_RS10195 2100294..2101166 + 873 WP_000879334.1 copper homeostasis membrane protein CopD -
M5S78_RS10200 2101179..2101520 + 342 WP_000976492.1 YebY family protein -
- 2101548..2101819 - 272 - - Antitoxin
- 2101678..2101781 + 104 - - Toxin
M5S78_RS10205 2101916..2102572 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
M5S78_RS10210 2102573..2102764 - 192 WP_001296140.1 YebW family protein -
M5S78_RS10215 2102869..2103105 - 237 WP_001295499.1 YebV family protein -
M5S78_RS10220 2103223..2104662 - 1440 WP_000057024.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255901 NZ_CP103626:2101678-2101781 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGGCCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT255901 NZ_CP103626:c2101819-2101548 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGCCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References