Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 855897..856425 Replicon chromosome
Accession NC_015942
Organism Acidithiobacillus ferrivorans SS3

Toxin (Protein)


Gene name parE Uniprot ID G0JMJ1
Locus tag ACIFE_RS03940 Protein ID WP_014028286.1
Coordinates 856135..856425 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID G0JMJ0
Locus tag ACIFE_RS03935 Protein ID WP_014028285.1
Coordinates 855897..856142 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACIFE_RS03920 851388..852200 - 813 WP_014028282.1 hypothetical protein -
ACIFE_RS03925 852197..853927 - 1731 WP_014028283.1 AAA family ATPase -
ACIFE_RS03930 853930..855780 - 1851 WP_014028284.1 restriction endonuclease subunit S -
ACIFE_RS03935 855897..856142 + 246 WP_014028285.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
ACIFE_RS03940 856135..856425 + 291 WP_014028286.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACIFE_RS03945 856483..859272 - 2790 WP_014028287.1 DEAD/DEAH box helicase family protein -
ACIFE_RS03950 859427..861115 - 1689 WP_014028288.1 putative DNA binding domain-containing protein -
ACIFE_RS16160 861087..861284 - 198 WP_014028289.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 842046..861284 19238


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(7-79)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11026.54 Da        Isoelectric Point: 6.9774

>T25590 WP_014028286.1 NC_015942:856135-856425 [Acidithiobacillus ferrivorans SS3]
MAEFRLTPAALRDLEGIWRYTAQQWGVAQAERYLDALNASFEDLAHAPLSAPACDDIRPGYRRHGVERHAVYYRVEAVTV
IVVRVLHERMDAPRHL

Download         Length: 291 bp

>T25590 NC_015942:856135-856425 [Acidithiobacillus ferrivorans SS3]
ATGGCTGAATTCCGCCTCACGCCAGCGGCCTTGCGTGATCTGGAAGGCATTTGGCGTTACACGGCGCAGCAGTGGGGTGT
GGCTCAGGCCGAACGTTACCTGGATGCACTGAATGCCAGTTTTGAAGACCTGGCTCACGCTCCACTTTCGGCGCCGGCGT
GCGACGACATCCGGCCAGGCTACCGACGACACGGGGTGGAACGCCACGCCGTGTACTACCGGGTCGAAGCGGTGACGGTA
ATTGTGGTGCGGGTGCTGCACGAACGCATGGATGCGCCGCGCCATCTGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9070.15 Da        Isoelectric Point: 6.4610

>AT25590 WP_014028285.1 NC_015942:855897-856142 [Acidithiobacillus ferrivorans SS3]
MATVRKTISLTDQQDGWIKAQIQAGHYTNDSEYIRDLIRREQERVAQLDALRAALIEGENSGAPQPFDVQAFKARMAATH
G

Download         Length: 246 bp

>AT25590 NC_015942:855897-856142 [Acidithiobacillus ferrivorans SS3]
ATGGCCACTGTGCGCAAAACCATCTCTCTCACCGACCAGCAGGATGGCTGGATCAAGGCCCAGATTCAGGCGGGGCATTA
CACCAACGACAGCGAATACATCCGTGATCTGATTCGCCGTGAGCAGGAGCGCGTGGCGCAGTTGGACGCGCTGCGTGCGG
CGTTGATCGAGGGCGAAAACAGCGGCGCGCCGCAGCCCTTTGATGTGCAGGCGTTCAAGGCGCGGATGGCCGCAACGCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1E7XRV5

Antitoxin

Source ID Structure
AlphaFold DB A0A1E7XRV7

References