Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4661711..4662227 Replicon chromosome
Accession NZ_CP103621
Organism Klebsiella pneumoniae strain 433

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M5S60_RS22660 Protein ID WP_040216106.1
Coordinates 4661711..4661995 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M5S60_RS22665 Protein ID WP_046654738.1
Coordinates 4661985..4662227 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S60_RS22635 (4657106) 4657106..4657369 - 264 WP_004152271.1 PTS sugar transporter subunit IIB -
M5S60_RS22640 (4657499) 4657499..4657672 + 174 WP_004872639.1 hypothetical protein -
M5S60_RS22645 (4657675) 4657675..4658418 + 744 WP_002886905.1 MurR/RpiR family transcriptional regulator -
M5S60_RS22650 (4658775) 4658775..4660913 + 2139 WP_004186701.1 anaerobic ribonucleoside-triphosphate reductase -
M5S60_RS22655 (4661243) 4661243..4661707 + 465 WP_032418146.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
M5S60_RS22660 (4661711) 4661711..4661995 - 285 WP_040216106.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M5S60_RS22665 (4661985) 4661985..4662227 - 243 WP_046654738.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M5S60_RS22670 (4662305) 4662305..4664215 - 1911 WP_023325426.1 PRD domain-containing protein -
M5S60_RS22675 (4664238) 4664238..4665392 - 1155 WP_040216103.1 lactonase family protein -
M5S60_RS22680 (4665459) 4665459..4666199 - 741 WP_004186692.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11097.94 Da        Isoelectric Point: 10.4962

>T255868 WP_040216106.1 NZ_CP103621:c4661995-4661711 [Klebsiella pneumoniae]
MTYELAFDPRAWREWQKPGETVKKQFKNKLQQIVQNPRIESTRLSDLPDCYKIKLKASGYRLVYQVRDSVVVVYVIAIGK
REKAAVYHQANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9049.54 Da        Isoelectric Point: 6.3340

>AT255868 WP_046654738.1 NZ_CP103621:c4662227-4661985 [Klebsiella pneumoniae]
MATLNVRLDDKLKKEAYAVLEKLDMTPTEAVRLLFQYIAENGRMPVKSMTISDGEAALLRTVRERLENPRTGVKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References