Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1900582..1900727 Replicon chromosome
Accession NZ_CP103614
Organism Klebsiella pneumoniae strain 3571

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1900618..1900720 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1900582..1900727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T29_RS09220 (M5T29_09220) 1895712..1897772 + 2061 WP_004148850.1 oligopeptidase B -
M5T29_RS09225 (M5T29_09225) 1897776..1898435 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5T29_RS09230 (M5T29_09230) 1898514..1898744 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T29_RS09235 (M5T29_09235) 1898857..1899231 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T29_RS09240 (M5T29_09240) 1899235..1900104 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
M5T29_RS09245 (M5T29_09245) 1900121..1900459 + 339 WP_002911404.1 YebY family protein -
- 1900582..1900727 - 146 - - Antitoxin
- 1900618..1900720 + 103 - - Toxin
M5T29_RS09250 (M5T29_09250) 1901095..1901238 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T29_RS09255 (M5T29_09255) 1901343..1902311 - 969 WP_004151446.1 VirK/YbjX family protein -
M5T29_RS09260 (M5T29_09260) 1902468..1903121 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
M5T29_RS09265 (M5T29_09265) 1903118..1903309 - 192 WP_002911395.1 YebW family protein -
M5T29_RS09270 (M5T29_09270) 1903407..1903646 - 240 WP_002911393.1 YebV family protein -
M5T29_RS09275 (M5T29_09275) 1903762..1905195 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255829 NZ_CP103614:1900618-1900720 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255829 NZ_CP103614:c1900727-1900582 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References