Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1911722..1911867 Replicon chromosome
Accession NZ_CP103605
Organism Klebsiella pneumoniae strain 4386

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1911758..1911860 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1911722..1911867 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S85_RS09195 1906852..1908912 + 2061 WP_048289976.1 oligopeptidase B -
M5S85_RS09200 1908916..1909575 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5S85_RS09205 1909654..1909884 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S85_RS09210 1909997..1910371 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S85_RS09215 1910375..1911244 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
M5S85_RS09220 1911261..1911599 + 339 WP_048289975.1 YebY family protein -
- 1911722..1911867 - 146 - - Antitoxin
- 1911758..1911860 + 103 - - Toxin
M5S85_RS09225 1912234..1912377 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S85_RS09230 1912482..1913450 - 969 WP_004151446.1 VirK/YbjX family protein -
M5S85_RS09235 1913607..1914260 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
M5S85_RS09240 1914257..1914448 - 192 WP_002911395.1 YebW family protein -
M5S85_RS09245 1914546..1914785 - 240 WP_002911393.1 YebV family protein -
M5S85_RS09250 1914901..1916334 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255779 NZ_CP103605:1911758-1911860 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255779 NZ_CP103605:c1911867-1911722 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References