Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1969497..1969768 Replicon chromosome
Accession NZ_CP103596
Organism Escherichia coli strain 4848

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1969627..1969730 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1969497..1969768 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T19_RS09515 1966052..1966714 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5T19_RS09520 1966738..1967394 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
M5T19_RS09525 1967496..1967726 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T19_RS09530 1967865..1968239 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5T19_RS09535 1968243..1969115 + 873 WP_046464082.1 copper homeostasis membrane protein CopD -
M5T19_RS09540 1969128..1969469 + 342 WP_000976476.1 YebY family protein -
- 1969497..1969768 - 272 - - Antitoxin
- 1969627..1969730 + 104 - - Toxin
M5T19_RS09545 1969865..1970521 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
M5T19_RS09550 1970522..1970713 - 192 WP_000457842.1 YebW family protein -
M5T19_RS09555 1970818..1971054 - 237 WP_001295499.1 YebV family protein -
M5T19_RS09560 1971172..1972611 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255758 NZ_CP103596:1969627-1969730 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT255758 NZ_CP103596:c1969768-1969497 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References