Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2205918..2206186 Replicon chromosome
Accession NZ_CP103592
Organism Escherichia coli O25b:H4-ST131 strain 4224

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2206046..2206148 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2205918..2206186 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S53_RS10605 2202471..2203133 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5S53_RS10610 2203157..2203813 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
M5S53_RS10615 2203915..2204145 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5S53_RS10620 2204284..2204658 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5S53_RS10625 2204662..2205534 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
M5S53_RS10630 2205547..2205888 + 342 WP_000976472.1 YebY family protein -
- 2205918..2206186 - 269 - - Antitoxin
- 2206046..2206148 + 103 - - Toxin
M5S53_RS10635 2206283..2206939 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
M5S53_RS10640 2206940..2207131 - 192 WP_001296140.1 YebW family protein -
M5S53_RS10645 2207236..2207472 - 237 WP_001295499.1 YebV family protein -
M5S53_RS10650 2207589..2209028 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255729 NZ_CP103592:2206046-2206148 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT255729 NZ_CP103592:c2206186-2205918 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References