Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943888..1944033 Replicon chromosome
Accession NZ_CP103586
Organism Klebsiella pneumoniae strain 4737

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943924..1944026 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943888..1944033 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T07_RS09520 1939018..1941078 + 2061 WP_004148850.1 oligopeptidase B -
M5T07_RS09525 1941082..1941741 - 660 WP_032435029.1 exodeoxyribonuclease X -
M5T07_RS09530 1941820..1942050 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T07_RS09535 1942163..1942537 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T07_RS09540 1942541..1943410 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5T07_RS09545 1943427..1943765 + 339 WP_002911404.1 YebY family protein -
- 1943888..1944033 - 146 - - Antitoxin
- 1943924..1944026 + 103 - - Toxin
M5T07_RS09550 1944401..1944544 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5T07_RS09555 1944649..1945617 - 969 WP_004151446.1 VirK/YbjX family protein -
M5T07_RS09560 1945774..1946427 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5T07_RS09565 1946424..1946615 - 192 WP_002911395.1 YebW family protein -
M5T07_RS09570 1946713..1946952 - 240 WP_002911393.1 YebV family protein -
M5T07_RS09575 1947068..1948501 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1873861..1948456 74595


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255680 NZ_CP103586:1943924-1944026 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255680 NZ_CP103586:c1944033-1943888 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References