Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3027168..3027824 Replicon chromosome
Accession NC_015856
Organism Collimonas fungivorans Ter331

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CFU_RS13130 Protein ID WP_041741980.1
Coordinates 3027168..3027578 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CFU_RS13135 Protein ID WP_041741982.1
Coordinates 3027606..3027824 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFU_RS13115 3022469..3025339 - 2871 WP_014006525.1 DUF2135 domain-containing protein -
CFU_RS13120 3025569..3026138 + 570 WP_148264998.1 sigma-70 family RNA polymerase sigma factor -
CFU_RS13125 3026135..3027130 + 996 WP_014006527.1 hypothetical protein -
CFU_RS13130 3027168..3027578 - 411 WP_041741980.1 type II toxin-antitoxin system VapC family toxin Toxin
CFU_RS13135 3027606..3027824 - 219 WP_041741982.1 DNA-binding protein Antitoxin
CFU_RS13140 3028066..3029031 - 966 WP_041741983.1 NAD-dependent epimerase/dehydratase family protein -
CFU_RS13145 3029056..3030279 - 1224 WP_014006531.1 glycine C-acetyltransferase -
CFU_RS13150 3030372..3030965 + 594 WP_041743449.1 XRE family transcriptional regulator -
CFU_RS13155 3031047..3031499 - 453 WP_041741985.1 glycine zipper 2TM domain-containing protein -
CFU_RS13160 3031841..3032086 + 246 WP_041741987.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15046.16 Da        Isoelectric Point: 6.4559

>T25568 WP_041741980.1 NC_015856:c3027578-3027168 [Collimonas fungivorans Ter331]
VYLLDTNVISESRKGKKANLGTQAFWRSVDLDAIYLPAQSIGEIRRGIEIVKRRGDSAQAKMLETWLQTLTTEYADRILS
FDDGCAQVWGCLMSADNQHPIDKQIAAIALIHSMTVVTRNTSDFIGTGVSLVNPFS

Download         Length: 411 bp

>T25568 NC_015856:c3027578-3027168 [Collimonas fungivorans Ter331]
GTGTATCTGCTAGATACCAATGTCATCAGCGAGTCCCGCAAAGGGAAAAAGGCCAATCTCGGAACGCAGGCGTTCTGGCG
CTCGGTTGACCTCGATGCGATTTATCTGCCGGCGCAAAGCATAGGCGAAATACGCCGCGGTATTGAAATCGTCAAGCGCC
GCGGCGATTCAGCACAGGCCAAAATGCTGGAGACATGGCTGCAGACGCTTACAACGGAATATGCGGATCGTATCCTGTCT
TTTGACGACGGTTGTGCCCAGGTGTGGGGGTGTTTGATGTCCGCCGACAATCAACATCCGATCGATAAGCAAATTGCCGC
GATCGCCTTGATCCATAGCATGACTGTCGTTACGCGTAACACCAGCGATTTTATCGGCACCGGGGTGAGCCTGGTAAATC
CGTTTTCCTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8169.25 Da        Isoelectric Point: 5.7012

>AT25568 WP_041741982.1 NC_015856:c3027824-3027606 [Collimonas fungivorans Ter331]
MATNLVVRNVEEELTLALKQQAAAHGRSAEAEHREILRAALQRPKRRSLVEFLLSMPDVGEDKDFDARNVQE

Download         Length: 219 bp

>AT25568 NC_015856:c3027824-3027606 [Collimonas fungivorans Ter331]
ATGGCGACCAACCTGGTGGTTAGAAACGTGGAAGAAGAGCTTACTTTGGCACTCAAGCAGCAGGCTGCTGCGCACGGCCG
CAGCGCCGAAGCCGAACACAGGGAAATCCTGCGGGCGGCGCTGCAGCGTCCGAAGCGGCGTTCGCTGGTGGAATTTTTAT
TGAGTATGCCGGATGTCGGAGAAGACAAGGACTTCGATGCGCGCAATGTTCAAGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References