Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1777618..1778211 Replicon chromosome
Accession NC_015856
Organism Collimonas fungivorans Ter331

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag CFU_RS07775 Protein ID WP_041741509.1
Coordinates 1777618..1777908 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFU_RS07780 Protein ID WP_014005485.1
Coordinates 1777918..1778211 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFU_RS07765 1772798..1775893 + 3096 WP_014005482.1 efflux RND transporter permease subunit -
CFU_RS07770 1775926..1777401 + 1476 WP_041741507.1 efflux transporter outer membrane subunit -
CFU_RS07775 1777618..1777908 + 291 WP_041741509.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFU_RS07780 1777918..1778211 + 294 WP_014005485.1 putative addiction module antidote protein Antitoxin
CFU_RS07785 1778641..1780548 + 1908 WP_041743122.1 threonine--tRNA ligase -
CFU_RS07790 1780609..1781133 + 525 WP_081466431.1 translation initiation factor IF-3 -
CFU_RS23745 1781329..1781526 + 198 WP_014005488.1 50S ribosomal protein L35 -
CFU_RS07795 1781550..1781909 + 360 WP_014005489.1 50S ribosomal protein L20 -
CFU_RS07800 1782069..1783087 + 1019 Protein_1578 phenylalanine--tRNA ligase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10786.62 Da        Isoelectric Point: 10.3161

>T25567 WP_041741509.1 NC_015856:1777618-1777908 [Collimonas fungivorans Ter331]
VKIIQTTPIFDHWFASLRDRSAKVRIQMRIDRAELGNFGDCAPVGEGVSEMRIHFGCGYRIYFVQRGDEMVVLLAGGGKS
TQSKDVKMALKLARKL

Download         Length: 291 bp

>T25567 NC_015856:1777618-1777908 [Collimonas fungivorans Ter331]
GTGAAGATTATTCAAACCACTCCGATATTTGATCATTGGTTTGCTTCATTGCGCGACCGCAGCGCCAAGGTGCGCATCCA
GATGCGCATTGATCGTGCCGAGCTGGGTAATTTTGGCGATTGCGCACCGGTCGGAGAGGGTGTTTCCGAGATGCGGATTC
ATTTTGGCTGCGGCTACCGCATATATTTTGTGCAGCGTGGCGATGAAATGGTGGTATTGCTTGCCGGTGGCGGGAAGTCG
ACACAAAGCAAGGACGTCAAGATGGCATTGAAGCTGGCGCGGAAACTTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10312.75 Da        Isoelectric Point: 6.2135

>AT25567 WP_014005485.1 NC_015856:1777918-1778211 [Collimonas fungivorans Ter331]
MGTIKLRQWDSAEHLQTGADIVAYFDACLEEAGDDPAFIAHALGNIARARGMSQVARDAGLARESLYKALSGEGNPEFGT
ILKVMKALGLRLHATAA

Download         Length: 294 bp

>AT25567 NC_015856:1777918-1778211 [Collimonas fungivorans Ter331]
ATGGGAACGATCAAACTGCGTCAGTGGGATTCTGCCGAGCATCTGCAAACCGGCGCCGATATCGTTGCCTATTTCGATGC
GTGTCTTGAAGAAGCGGGCGACGATCCTGCCTTCATCGCGCATGCCTTGGGCAATATTGCGCGCGCACGCGGCATGAGCC
AGGTGGCGCGGGATGCCGGCCTGGCGCGCGAAAGCCTGTATAAGGCGTTGTCCGGCGAGGGCAATCCAGAGTTCGGGACC
ATTCTGAAAGTCATGAAAGCGCTTGGGCTGAGGCTGCATGCGACGGCGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References