Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1892483..1892628 Replicon chromosome
Accession NZ_CP103582
Organism Klebsiella pneumoniae strain 1498

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1892519..1892621 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1892483..1892628 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S97_RS09145 (M5S97_09145) 1887613..1889673 + 2061 WP_004151449.1 oligopeptidase B -
M5S97_RS09150 (M5S97_09150) 1889677..1890336 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5S97_RS09155 (M5S97_09155) 1890415..1890645 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S97_RS09160 (M5S97_09160) 1890758..1891132 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S97_RS09165 (M5S97_09165) 1891136..1892005 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
M5S97_RS09170 (M5S97_09170) 1892022..1892360 + 339 WP_016529031.1 YebY family protein -
- 1892483..1892628 - 146 - - Antitoxin
- 1892519..1892621 + 103 - - Toxin
M5S97_RS09175 (M5S97_09175) 1892996..1893139 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S97_RS09180 (M5S97_09180) 1893244..1894212 - 969 WP_004151446.1 VirK/YbjX family protein -
M5S97_RS09185 (M5S97_09185) 1894369..1895022 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
M5S97_RS09190 (M5S97_09190) 1895019..1895210 - 192 WP_002911395.1 YebW family protein -
M5S97_RS09195 (M5S97_09195) 1895308..1895547 - 240 WP_002911393.1 YebV family protein -
M5S97_RS09200 (M5S97_09200) 1895663..1897096 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255663 NZ_CP103582:1892519-1892621 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255663 NZ_CP103582:c1892628-1892483 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References