Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1972333..1972542 Replicon chromosome
Accession NZ_CP103577
Organism Enterobacter hormaechei strain 4285

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1972426..1972529 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1972333..1972542 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S64_RS09345 (M5S64_09345) 1968870..1969532 - 663 WP_015570288.1 exodeoxyribonuclease X -
M5S64_RS09350 (M5S64_09350) 1969557..1970207 - 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
M5S64_RS09355 (M5S64_09355) 1970319..1970549 - 231 WP_003859784.1 DNA polymerase III subunit theta -
M5S64_RS09360 (M5S64_09360) 1970687..1971058 + 372 WP_017384342.1 CopC domain-containing protein YobA -
M5S64_RS09365 (M5S64_09365) 1971060..1971929 + 870 WP_045338991.1 copper homeostasis membrane protein CopD -
M5S64_RS09370 (M5S64_09370) 1971946..1972284 + 339 WP_003859787.1 YebY family protein -
- 1972333..1972542 - 210 - - Antitoxin
M5S64_RS09375 (M5S64_09375) 1972410..1972607 - 198 WP_045338990.1 hypothetical protein -
- 1972426..1972529 + 104 - - Toxin
M5S64_RS09380 (M5S64_09380) 1972653..1973633 - 981 WP_039270562.1 VirK/YbjX family protein -
M5S64_RS09385 (M5S64_09385) 1973801..1974445 + 645 WP_017384338.1 protein-serine/threonine phosphatase -
M5S64_RS09390 (M5S64_09390) 1974480..1974719 - 240 WP_003859885.1 YebV family protein -
M5S64_RS09395 (M5S64_09395) 1974826..1976274 - 1449 WP_195207010.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255635 NZ_CP103577:1972426-1972529 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 210 bp

>AT255635 NZ_CP103577:c1972542-1972333 [Enterobacter hormaechei]
TTTTCAAGCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCA
AAAGTGGTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References