Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 865660..866317 Replicon chromosome
Accession NZ_CP103577
Organism Enterobacter hormaechei strain 4285

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag M5S64_RS04150 Protein ID WP_045340098.1
Coordinates 865907..866317 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag M5S64_RS04145 Protein ID WP_003863437.1
Coordinates 865660..865926 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S64_RS04125 (M5S64_04125) 861066..862499 - 1434 WP_023295383.1 6-phospho-beta-glucosidase BglA -
M5S64_RS04130 (M5S64_04130) 862616..863347 - 732 WP_015571796.1 MurR/RpiR family transcriptional regulator -
M5S64_RS04135 (M5S64_04135) 863614..864273 + 660 WP_003863433.1 hemolysin III family protein -
M5S64_RS04140 (M5S64_04140) 864385..865365 - 981 WP_022649306.1 tRNA-modifying protein YgfZ -
M5S64_RS04145 (M5S64_04145) 865660..865926 + 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
M5S64_RS04150 (M5S64_04150) 865907..866317 + 411 WP_045340098.1 protein YgfX Toxin
M5S64_RS04155 (M5S64_04155) 866319..866840 - 522 WP_015571793.1 flavodoxin FldB -
M5S64_RS04160 (M5S64_04160) 866942..867838 + 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
M5S64_RS04165 (M5S64_04165) 867867..868580 + 714 WP_006811871.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
M5S64_RS04170 (M5S64_04170) 868586..870319 + 1734 WP_017382886.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16249.14 Da        Isoelectric Point: 11.7121

>T255632 WP_045340098.1 NZ_CP103577:865907-866317 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWGMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT255632 WP_003863437.1 NZ_CP103577:865660-865926 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References