Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2006365..2006510 Replicon chromosome
Accession NZ_CP103567
Organism Klebsiella pneumoniae strain 4680

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2006401..2006503 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2006365..2006510 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S58_RS09700 2001495..2003555 + 2061 WP_048289976.1 oligopeptidase B -
M5S58_RS09705 2003559..2004218 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5S58_RS09710 2004297..2004527 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S58_RS09715 2004640..2005014 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S58_RS09720 2005018..2005887 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
M5S58_RS09725 2005904..2006242 + 339 WP_048289975.1 YebY family protein -
- 2006365..2006510 - 146 - - Antitoxin
- 2006401..2006503 + 103 - - Toxin
M5S58_RS09730 2006877..2007020 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S58_RS09735 2007125..2008093 - 969 WP_004151446.1 VirK/YbjX family protein -
M5S58_RS09740 2008250..2008903 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
M5S58_RS09745 2008900..2009091 - 192 WP_002911395.1 YebW family protein -
M5S58_RS09750 2009189..2009428 - 240 WP_002911393.1 YebV family protein -
M5S58_RS09755 2009544..2010977 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255596 NZ_CP103567:2006401-2006503 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255596 NZ_CP103567:c2006510-2006365 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References