Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1991039..1991184 Replicon chromosome
Accession NZ_CP103560
Organism Klebsiella pneumoniae strain 5165

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1991075..1991177 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1991039..1991184 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R31_RS09610 1986169..1988229 + 2061 WP_004148850.1 oligopeptidase B -
M5R31_RS09615 1988233..1988892 - 660 WP_032435029.1 exodeoxyribonuclease X -
M5R31_RS09620 1988971..1989201 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5R31_RS09625 1989314..1989688 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5R31_RS09630 1989692..1990561 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5R31_RS09635 1990578..1990916 + 339 WP_002911404.1 YebY family protein -
- 1991039..1991184 - 146 - - Antitoxin
- 1991075..1991177 + 103 - - Toxin
M5R31_RS09640 1991552..1991695 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5R31_RS09645 1991800..1992768 - 969 WP_004151446.1 VirK/YbjX family protein -
M5R31_RS09650 1992925..1993578 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5R31_RS09655 1993575..1993766 - 192 WP_002911395.1 YebW family protein -
M5R31_RS09660 1993864..1994103 - 240 WP_002911393.1 YebV family protein -
M5R31_RS09665 1994219..1995652 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255543 NZ_CP103560:1991075-1991177 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255543 NZ_CP103560:c1991184-1991039 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References