Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2383001..2383269 Replicon chromosome
Accession NZ_CP103557
Organism Escherichia coli O25b:H4-ST131 strain 4993

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2383129..2383231 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2383001..2383269 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T49_RS11860 2379554..2380216 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5T49_RS11865 2380240..2380896 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
M5T49_RS11870 2380998..2381228 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T49_RS11875 2381367..2381741 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5T49_RS11880 2381745..2382617 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
M5T49_RS11885 2382630..2382971 + 342 WP_000976472.1 YebY family protein -
- 2383001..2383269 - 269 - - Antitoxin
- 2383129..2383231 + 103 - - Toxin
M5T49_RS11890 2383366..2384022 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
M5T49_RS11895 2384023..2384214 - 192 WP_001296140.1 YebW family protein -
M5T49_RS11900 2384319..2384555 - 237 WP_001295499.1 YebV family protein -
M5T49_RS11905 2384672..2386111 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255490 NZ_CP103557:2383129-2383231 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT255490 NZ_CP103557:c2383269-2383001 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References