Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2199608..2199776 Replicon chromosome
Accession NZ_CP103554
Organism Klebsiella michiganensis strain 5088

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2199666..2199769 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2199608..2199776 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5R35_RS10455 (M5R35_10455) 2194735..2196795 + 2061 WP_014229840.1 oligopeptidase B -
M5R35_RS10460 (M5R35_10460) 2196802..2197461 - 660 WP_014229839.1 exodeoxyribonuclease X -
M5R35_RS10465 (M5R35_10465) 2197540..2197770 - 231 WP_004103351.1 DNA polymerase III subunit theta -
M5R35_RS10470 (M5R35_10470) 2197906..2198280 + 375 WP_014229838.1 CopC domain-containing protein YobA -
M5R35_RS10475 (M5R35_10475) 2198285..2199154 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
M5R35_RS10480 (M5R35_10480) 2199171..2199509 + 339 WP_004103344.1 YebY family protein -
- 2199608..2199776 - 169 - - Antitoxin
- 2199666..2199769 + 104 - - Toxin
M5R35_RS10485 (M5R35_10485) 2199894..2200853 - 960 WP_014229836.1 spore coat protein U domain-containing protein -
M5R35_RS10490 (M5R35_10490) 2200868..2203198 - 2331 WP_014229835.1 fimbria/pilus outer membrane usher protein -
M5R35_RS10495 (M5R35_10495) 2203201..2203965 - 765 WP_014229834.1 fimbria/pilus periplasmic chaperone -
M5R35_RS10500 (M5R35_10500) 2203984..2204502 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255472 NZ_CP103554:2199666-2199769 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT255472 NZ_CP103554:c2199776-2199608 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References