Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002432..2002577 Replicon chromosome
Accession NZ_CP103548
Organism Klebsiella pneumoniae strain 3987

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002439..2002541 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002432..2002577 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T27_RS09800 1997964..1999397 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
M5T27_RS09805 1999513..1999752 + 240 WP_002911393.1 YebV family protein -
M5T27_RS09810 1999850..2000041 + 192 WP_002911395.1 YebW family protein -
M5T27_RS09815 2000038..2000691 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
M5T27_RS09820 2000848..2001816 + 969 WP_004151446.1 VirK/YbjX family protein -
M5T27_RS09825 2001921..2002064 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2002432..2002577 + 146 - - Antitoxin
- 2002439..2002541 - 103 - - Toxin
M5T27_RS09830 2002700..2003038 - 339 WP_002911404.1 YebY family protein -
M5T27_RS09835 2003055..2003924 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
M5T27_RS09840 2003928..2004302 - 375 WP_004151448.1 CopC domain-containing protein YobA -
M5T27_RS09845 2004415..2004645 + 231 WP_002911406.1 DNA polymerase III subunit theta -
M5T27_RS09850 2004724..2005383 + 660 WP_032435029.1 exodeoxyribonuclease X -
M5T27_RS09855 2005387..2007447 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255437 NZ_CP103548:c2002541-2002439 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255437 NZ_CP103548:2002432-2002577 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References