Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4256607..4257104 | Replicon | chromosome |
Accession | NZ_CP103540 | ||
Organism | Escherichia coli strain 5264 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | M5S66_RS20665 | Protein ID | WP_001173343.1 |
Coordinates | 4256607..4256780 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | L4JK92 |
Locus tag | M5S66_RS20670 | Protein ID | WP_000398619.1 |
Coordinates | 4256808..4257104 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
M5S66_RS20655 (4253277) | 4253277..4254734 | + | 1458 | WP_000856829.1 | dipeptide/tripeptide permease DtpC | - |
M5S66_RS20660 (4254971) | 4254971..4256488 | + | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
M5S66_RS20665 (4256607) | 4256607..4256780 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
M5S66_RS20670 (4256808) | 4256808..4257104 | - | 297 | WP_000398619.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
M5S66_RS20675 (4257331) | 4257331..4257603 | - | 273 | WP_000405651.1 | GNAT family N-acetyltransferase | - |
M5S66_RS20680 (4257615) | 4257615..4257845 | - | 231 | WP_000371704.1 | 4Fe-4S mono-cluster protein YjdI | - |
M5S66_RS20685 (4258026) | 4258026..4259657 | + | 1632 | WP_001216477.1 | sensor histidine kinase | - |
M5S66_RS20690 (4259654) | 4259654..4260373 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QBH6 |