Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2214237..2214508 Replicon chromosome
Accession NZ_CP103529
Organism Escherichia coli strain 5270

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2214367..2214470 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2214237..2214508 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T24_RS10605 2210792..2211454 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5T24_RS10610 2211478..2212134 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
M5T24_RS10615 2212236..2212466 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T24_RS10620 2212605..2212979 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5T24_RS10625 2212983..2213855 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
M5T24_RS10630 2213868..2214209 + 342 WP_000976476.1 YebY family protein -
- 2214237..2214508 - 272 - - Antitoxin
- 2214367..2214470 + 104 - - Toxin
M5T24_RS10635 2214605..2215261 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
M5T24_RS10640 2215262..2215453 - 192 WP_000457842.1 YebW family protein -
M5T24_RS10645 2215558..2215794 - 237 WP_001295499.1 YebV family protein -
M5T24_RS10650 2215912..2217351 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255334 NZ_CP103529:2214367-2214470 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT255334 NZ_CP103529:c2214508-2214237 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References