Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2039500..2039645 Replicon chromosome
Accession NZ_CP103512
Organism Klebsiella pneumoniae strain 5531

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2039536..2039638 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2039500..2039645 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5S57_RS09740 2034630..2036690 + 2061 WP_004151449.1 oligopeptidase B -
M5S57_RS09745 2036694..2037353 - 660 WP_002911407.1 exodeoxyribonuclease X -
M5S57_RS09750 2037432..2037662 - 231 WP_002911406.1 DNA polymerase III subunit theta -
M5S57_RS09755 2037775..2038149 + 375 WP_004151448.1 CopC domain-containing protein YobA -
M5S57_RS09760 2038153..2039022 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
M5S57_RS09765 2039039..2039377 + 339 WP_002911404.1 YebY family protein -
- 2039500..2039645 - 146 - - Antitoxin
- 2039536..2039638 + 103 - - Toxin
M5S57_RS09770 2040013..2040156 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
M5S57_RS09775 2040261..2041229 - 969 WP_014907334.1 VirK/YbjX family protein -
M5S57_RS09780 2041386..2042039 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
M5S57_RS09785 2042036..2042227 - 192 WP_002911395.1 YebW family protein -
M5S57_RS09790 2042325..2042564 - 240 WP_002911393.1 YebV family protein -
M5S57_RS09795 2042680..2044113 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255248 NZ_CP103512:2039536-2039638 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT255248 NZ_CP103512:c2039645-2039500 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References