Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2044406..2044551 | Replicon | chromosome |
| Accession | NZ_CP103503 | ||
| Organism | Klebsiella pneumoniae strain 5547 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2044442..2044544 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2044406..2044551 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5R16_RS10230 | 2039536..2041596 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| M5R16_RS10235 | 2041600..2042259 | - | 660 | WP_043906809.1 | exodeoxyribonuclease X | - |
| M5R16_RS10240 | 2042338..2042568 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| M5R16_RS10245 | 2042681..2043055 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| M5R16_RS10250 | 2043059..2043928 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| M5R16_RS10255 | 2043945..2044283 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2044406..2044551 | - | 146 | - | - | Antitoxin |
| - | 2044442..2044544 | + | 103 | - | - | Toxin |
| M5R16_RS10260 | 2044920..2045063 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| M5R16_RS10265 | 2045168..2046136 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| M5R16_RS10270 | 2046293..2046946 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| M5R16_RS10275 | 2046943..2047134 | - | 192 | WP_002911395.1 | YebW family protein | - |
| M5R16_RS10280 | 2047232..2047471 | - | 240 | WP_002911393.1 | YebV family protein | - |
| M5R16_RS10285 | 2047587..2049020 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1971351..2048975 | 77624 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T255197 NZ_CP103503:2044442-2044544 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT255197 NZ_CP103503:c2044551-2044406 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
