Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1649653..1650566 Replicon chromosome
Accession NZ_CP103494
Organism Enterobacter hormaechei strain 70

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M5T15_RS07880 Protein ID WP_045142243.1
Coordinates 1649653..1650126 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag M5T15_RS07885 Protein ID WP_023296216.1
Coordinates 1650123..1650566 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T15_RS07860 (M5T15_07860) 1645812..1647122 + 1311 WP_045142247.1 type I-F CRISPR-associated protein Csy1 -
M5T15_RS07865 (M5T15_07865) 1647119..1648054 + 936 WP_045142246.1 type I-F CRISPR-associated protein Csy2 -
M5T15_RS07870 (M5T15_07870) 1648068..1649066 + 999 WP_045142245.1 type I-F CRISPR-associated protein Csy3 -
M5T15_RS07875 (M5T15_07875) 1649076..1649630 + 555 WP_045142244.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
M5T15_RS07880 (M5T15_07880) 1649653..1650126 - 474 WP_045142243.1 RES domain-containing protein Toxin
M5T15_RS07885 (M5T15_07885) 1650123..1650566 - 444 WP_023296216.1 DUF2384 domain-containing protein Antitoxin
M5T15_RS07890 (M5T15_07890) 1651905..1652123 - 219 WP_002211347.1 translation initiation factor IF-1 -
M5T15_RS07895 (M5T15_07895) 1652408..1653112 - 705 WP_040117448.1 leucyl/phenylalanyl-tRNA--protein transferase -
M5T15_RS07900 (M5T15_07900) 1653158..1654879 - 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-145)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17569.93 Da        Isoelectric Point: 5.1018

>T255169 WP_045142243.1 NZ_CP103494:c1650126-1649653 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHKALNSVELMPFNFDTRLAEKTAP

Download         Length: 474 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16512.81 Da        Isoelectric Point: 6.4819

>AT255169 WP_023296216.1 NZ_CP103494:c1650566-1650123 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References