Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 109855..110574 Replicon chromosome
Accession NZ_CP103494
Organism Enterobacter hormaechei strain 70

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag M5T15_RS00530 Protein ID WP_040117033.1
Coordinates 109855..110175 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag M5T15_RS00535 Protein ID WP_032620726.1
Coordinates 110209..110574 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T15_RS00510 (M5T15_00510) 105824..106165 - 342 WP_006812446.1 SymE family type I addiction module toxin -
M5T15_RS00515 (M5T15_00515) 106294..106455 + 162 WP_065419814.1 YlcI/YnfO family protein -
M5T15_RS00520 (M5T15_00520) 106640..107380 + 741 WP_063151591.1 hypothetical protein -
M5T15_RS00525 (M5T15_00525) 107377..109662 + 2286 WP_062934147.1 DEAD/DEAH box helicase -
M5T15_RS00530 (M5T15_00530) 109855..110175 - 321 WP_040117033.1 TA system toxin CbtA family protein Toxin
M5T15_RS00535 (M5T15_00535) 110209..110574 - 366 WP_032620726.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
M5T15_RS00540 (M5T15_00540) 110606..110827 - 222 WP_032620724.1 DUF987 domain-containing protein -
M5T15_RS00545 (M5T15_00545) 110836..111306 - 471 WP_040117034.1 DNA repair protein RadC -
M5T15_RS00550 (M5T15_00550) 111376..112197 - 822 WP_032620720.1 DUF932 domain-containing protein -
M5T15_RS00555 (M5T15_00555) 112890..113729 - 840 WP_049125417.1 hypothetical protein -
M5T15_RS00560 (M5T15_00560) 113842..114276 - 435 WP_044488933.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 101849..136597 34748


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-104)

Antitoxin

Antitoxin CbeA

(18-116)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12206.77 Da        Isoelectric Point: 5.9558

>T255166 WP_040117033.1 NZ_CP103494:c110175-109855 [Enterobacter hormaechei]
MHISTVPATVTVSSRLSPVQVWQKLLTYILEHHYGLTINDTPFSNDTTIQEHIEAGVNLTDAVNFLVERFELVRIDQKGF
SWQDQEPWITSLDVHRAQYNLGLKRS

Download         Length: 321 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13574.29 Da        Isoelectric Point: 6.4673

>AT255166 WP_032620726.1 NZ_CP103494:c110574-110209 [Enterobacter hormaechei]
MQSTTISGTSAENTSCLQWELKRNITPCFGARLVQESNRLYFLADRAGFNGSFSDDEALRLDQAFPLMMKQLERMLTAGE
LDPRSQHCVTRHHNGLTCEADTLGSHGYVYIAIYPQSALTR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References