Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4805101..4805572 Replicon chromosome
Accession NZ_CP103487
Organism Klebsiella quasipneumoniae subsp. quasipneumoniae strain 5463

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M5T26_RS23330 Protein ID WP_023291758.1
Coordinates 4805101..4805340 (-) Length 80 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1C1EW86
Locus tag M5T26_RS23335 Protein ID WP_023291757.1
Coordinates 4805330..4805572 (-) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T26_RS23320 (4802054) 4802054..4804192 + 2139 WP_004206513.1 anaerobic ribonucleoside-triphosphate reductase -
M5T26_RS23325 (4804588) 4804588..4805052 + 465 WP_012969085.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
M5T26_RS23330 (4805101) 4805101..4805340 - 240 WP_023291758.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M5T26_RS23335 (4805330) 4805330..4805572 - 243 WP_023291757.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
M5T26_RS23340 (4805650) 4805650..4807560 - 1911 WP_044525201.1 PRD domain-containing protein -
M5T26_RS23345 (4807583) 4807583..4808734 - 1152 WP_023291755.1 lactonase family protein -
M5T26_RS23350 (4808801) 4808801..4809541 - 741 WP_017900574.1 KDGP aldolase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 80 a.a.        Molecular weight: 9162.72 Da        Isoelectric Point: 10.1315

>T255163 WP_023291758.1 NZ_CP103487:c4805340-4805101 [Klebsiella quasipneumoniae subsp. quasipneumoniae]
MTYELAFDPRAWREWQKLGETIKKQFKNKLQQVVQNPRIASASLSDLPDCYKIKLKASGYRLVYQVRDSVVVVYVIAIG

Download         Length: 240 bp


Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9119.58 Da        Isoelectric Point: 4.8146

>AT255163 WP_023291757.1 NZ_CP103487:c4805572-4805330 [Klebsiella quasipneumoniae subsp. quasipneumoniae]
MATLNVRLDDKLKKEAYAVLEKLDMTPTEAVRLLFQYIAENGRMPVKSMTISDSEAALLRTVRERLENPQPEVKVSLDDL

Download         Length: 243 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A1C1EW86

References