Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2272052..2272323 Replicon chromosome
Accession NZ_CP103479
Organism Escherichia coli strain 4621

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2272182..2272285 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2272052..2272323 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T46_RS10765 2268607..2269269 - 663 WP_000944239.1 exodeoxyribonuclease X -
M5T46_RS10770 2269293..2269949 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
M5T46_RS10775 2270051..2270281 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T46_RS10780 2270420..2270794 + 375 WP_000168749.1 CopC domain-containing protein YobA -
M5T46_RS10785 2270798..2271670 + 873 WP_000879329.1 copper homeostasis membrane protein CopD -
M5T46_RS10790 2271683..2272024 + 342 WP_000976490.1 YebY family protein -
- 2272052..2272323 - 272 - - Antitoxin
- 2272182..2272285 + 104 - - Toxin
M5T46_RS10795 2272420..2273076 + 657 WP_000812713.1 protein-serine/threonine phosphatase -
M5T46_RS10800 2273077..2273268 - 192 WP_001296140.1 YebW family protein -
M5T46_RS10805 2273373..2273609 - 237 WP_001295499.1 YebV family protein -
M5T46_RS10810 2273727..2275166 - 1440 WP_024176277.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2264742..2288163 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T255131 NZ_CP103479:2272182-2272285 [Escherichia coli]
GGCAAGGCATCTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT255131 NZ_CP103479:c2272323-2272052 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGATGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References