255063

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2074359..2074875 Replicon chromosome
Accession NZ_CP103450
Organism Erwinia pyrifoliae strain CP201179

Toxin (Protein)


Gene name relE Uniprot ID D2T7S6
Locus tag NYP81_RS09980 Protein ID WP_012669379.1
Coordinates 2074591..2074875 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D2T7S5
Locus tag NYP81_RS09975 Protein ID WP_012669378.1
Coordinates 2074359..2074601 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP81_RS09960 (NYP81_09960) 2069688..2070056 - 369 WP_259818773.1 helix-turn-helix transcriptional regulator -
NYP81_RS09965 (NYP81_09965) 2070157..2072844 + 2688 WP_259818781.1 CHC2 zinc finger domain-containing protein -
NYP81_RS09970 (NYP81_09970) 2073043..2074098 + 1056 WP_259818775.1 site-specific tyrosine recombinase XerC -
NYP81_RS09975 (NYP81_09975) 2074359..2074601 + 243 WP_012669378.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NYP81_RS09980 (NYP81_09980) 2074591..2074875 + 285 WP_012669379.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP81_RS09990 (NYP81_09990) 2076834..2077094 + 261 WP_259818784.1 hypothetical protein -
NYP81_RS09995 (NYP81_09995) 2077141..2077611 + 471 WP_259818785.1 hypothetical protein -
NYP81_RS10000 (NYP81_10000) 2077613..2077969 + 357 WP_259817771.1 hypothetical protein -
NYP81_RS10005 (NYP81_10005) 2078037..2078339 - 303 WP_259817772.1 type I toxin-antitoxin system SymE family toxin -
NYP81_RS10010 (NYP81_10010) 2078414..2078818 - 405 WP_259817774.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2062222..2093004 30782


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11123.03 Da        Isoelectric Point: 10.3769

>T255063 WP_012669379.1 NZ_CP103450:2074591-2074875 [Erwinia pyrifoliae]
MSYELVFDPRALKEWKKLGATVREQFKKKLAEVLVNPRVESARLREYPDCYKIKLKSSGYRLVYQVQDEQLVVFVVATGK
RERLQVYRDAGKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9070.45 Da        Isoelectric Point: 4.6310

>AT255063 WP_012669378.1 NZ_CP103450:2074359-2074601 [Erwinia pyrifoliae]
MATLNVRLDDKLKSKAYAVLDELDVSPTEAVRLLFQYIAENERLPLKTLTVSDEEDALLKTVRERLASPQKGIRVTLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2T7S6

Antitoxin

Source ID Structure
AlphaFold DB D2T7S5

References