Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 31912..32572 Replicon chromosome
Accession NZ_CP103450
Organism Erwinia pyrifoliae strain CP201179

Toxin (Protein)


Gene name cptA Uniprot ID D2T6A5
Locus tag NYP81_RS00175 Protein ID WP_014539414.1
Coordinates 32159..32572 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NYP81_RS00170 Protein ID WP_012669171.1
Coordinates 31912..32178 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP81_RS00150 (NYP81_00150) 28997..29125 + 129 Protein_28 SDR family oxidoreductase -
NYP81_RS00155 (NYP81_00155) 29219..29827 - 609 WP_012669174.1 HD domain-containing protein -
NYP81_RS00160 (NYP81_00160) 30040..30699 + 660 WP_012669173.1 hemolysin III family protein -
NYP81_RS00165 (NYP81_00165) 30700..31686 - 987 WP_012669172.1 tRNA-modifying protein YgfZ -
NYP81_RS00170 (NYP81_00170) 31912..32178 + 267 WP_012669171.1 FAD assembly factor SdhE Antitoxin
NYP81_RS00175 (NYP81_00175) 32159..32572 + 414 WP_014539414.1 protein YgfX Toxin
NYP81_RS00180 (NYP81_00180) 32696..33214 - 519 WP_012669169.1 flavodoxin FldB -
NYP81_RS00185 (NYP81_00185) 33260..34213 - 954 WP_259819257.1 DMT family transporter -
NYP81_RS00190 (NYP81_00190) 34490..35383 + 894 WP_014543356.1 site-specific tyrosine recombinase XerD -
NYP81_RS00195 (NYP81_00195) 35429..36133 + 705 WP_259819258.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16057.13 Da        Isoelectric Point: 12.3470

>T255057 WP_014539414.1 NZ_CP103450:32159-32572 [Erwinia pyrifoliae]
VVLWQCELRQSKLAQRLSLLLHGAVMLALLLPAWPASAGLVRMLLLVLVLLECIRSRRRIRRRQGDVALLGGHALRWRQR
EWRILSRPWLTRQAILLSLRDAKGERERLWLFADGMADSHWRRLRMQLLNNKEQGNG

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10482.07 Da        Isoelectric Point: 6.4605

>AT255057 WP_012669171.1 NZ_CP103450:31912-32178 [Erwinia pyrifoliae]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDGDKRLFVRLLESDDPDLFNWLMNHGEPADAELKRMVLLIQQRN
KQRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2T6A5

Antitoxin

Source ID Structure

References