Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 603980..604640 Replicon chromosome
Accession NZ_CP103445
Organism Erwinia pyrifoliae strain CP201486

Toxin (Protein)


Gene name cptA Uniprot ID D2T6A5
Locus tag NYP84_RS02810 Protein ID WP_014539414.1
Coordinates 604227..604640 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NYP84_RS02805 Protein ID WP_012669171.1
Coordinates 603980..604246 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP84_RS02785 (NYP84_02785) 600985..601194 + 210 WP_259816865.1 SDR family oxidoreductase -
NYP84_RS02790 (NYP84_02790) 601288..601896 - 609 WP_012669174.1 HD domain-containing protein -
NYP84_RS02795 (NYP84_02795) 602108..602767 + 660 WP_012669173.1 hemolysin III family protein -
NYP84_RS02800 (NYP84_02800) 602768..603754 - 987 WP_259826094.1 tRNA-modifying protein YgfZ -
NYP84_RS02805 (NYP84_02805) 603980..604246 + 267 WP_012669171.1 FAD assembly factor SdhE Antitoxin
NYP84_RS02810 (NYP84_02810) 604227..604640 + 414 WP_014539414.1 protein YgfX Toxin
NYP84_RS02815 (NYP84_02815) 604764..605282 - 519 WP_012669169.1 flavodoxin FldB -
NYP84_RS02820 (NYP84_02820) 605328..606281 - 954 WP_259826095.1 DMT family transporter -
NYP84_RS02825 (NYP84_02825) 606607..607500 + 894 WP_014543356.1 site-specific tyrosine recombinase XerD -
NYP84_RS02830 (NYP84_02830) 607546..608250 + 705 WP_012669166.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16057.13 Da        Isoelectric Point: 12.3470

>T255047 WP_014539414.1 NZ_CP103445:604227-604640 [Erwinia pyrifoliae]
VVLWQCELRQSKLAQRLSLLLHGAVMLALLLPAWPASAGLVRMLLLVLVLLECIRSRRRIRRRQGDVALLGGHALRWRQR
EWRILSRPWLTRQAILLSLRDAKGERERLWLFADGMADSHWRRLRMQLLNNKEQGNG

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10482.07 Da        Isoelectric Point: 6.4605

>AT255047 WP_012669171.1 NZ_CP103445:603980-604246 [Erwinia pyrifoliae]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDGDKRLFVRLLESDDPDLFNWLMNHGEPADAELKRMVLLIQQRN
KQRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2T6A5

Antitoxin

Source ID Structure

References