Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2903694..2904354 Replicon chromosome
Accession NC_015761
Organism Salmonella bongori NCTC 12419

Toxin (Protein)


Gene name cptA Uniprot ID S5NC56
Locus tag SBG_RS13610 Protein ID WP_000244759.1
Coordinates 2903694..2904107 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag SBG_RS13615 Protein ID WP_000351186.1
Coordinates 2904088..2904354 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SBG_RS13590 2899636..2901369 - 1734 WP_000813377.1 single-stranded-DNA-specific exonuclease RecJ -
SBG_RS13595 2901375..2902088 - 714 WP_000745612.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
SBG_RS13600 2902112..2903008 - 897 WP_000806655.1 site-specific tyrosine recombinase XerD -
SBG_RS13605 2903121..2903642 + 522 WP_001055887.1 flavodoxin FldB -
SBG_RS13610 2903694..2904107 - 414 WP_000244759.1 protein YgfX Toxin
SBG_RS13615 2904088..2904354 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
SBG_RS13625 2904601..2905581 + 981 WP_000896119.1 tRNA-modifying protein YgfZ -
SBG_RS13630 2905632..2906291 - 660 WP_024135108.1 hemolysin III family protein -
SBG_RS13635 2906455..2906766 - 312 WP_015702996.1 N(4)-acetylcytidine aminohydrolase -
SBG_RS13640 2906924..2908357 + 1434 WP_000737109.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16190.13 Da        Isoelectric Point: 9.4274

>T25504 WP_000244759.1 NC_015761:c2904107-2903694 [Salmonella bongori NCTC 12419]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMMLLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGE
DWVLLRPPWLLNSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRVMLQQPLSGQH

Download         Length: 414 bp

>T25504 NC_015761:c2904107-2903694 [Salmonella bongori NCTC 12419]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTAATTTTATTGATGCCCTGGCCGTTGAGTTATACCCCATTGTGGATGATGCTACTGTCGCTGGTGGTGTTTGACTGCG
TTCGTAGTCAGCGCCGGATTAATACCTGTCAGGGAGAGATCAAGCTGCTAATGGATGGGCGCTTACGCTGGCAGGGGGAA
GACTGGGTGCTCCTGCGCCCGCCCTGGTTACTGAACAGCGGGATGGTGTTGCGTTTACGCGCCGAGTCCGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAGGCGGAATGGCGTGAGTTACGCCGTGTCATGTTGCAACAACCACTAT
CGGGCCAACACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT25504 WP_000351186.1 NC_015761:c2904354-2904088 [Salmonella bongori NCTC 12419]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT25504 NC_015761:c2904354-2904088 [Salmonella bongori NCTC 12419]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGCGACGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTGATGAATCACGGTAAACCGGCTGACGCTGAGCTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S5NC56

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References